NBCUniversal is set to undergo major changes in its C-suite and in its TV business, with the company reorganizing its executive ranks in connection with its plan to spin off most of its cable networks.

The portfolio, which includes MSNBC, CNBC, E!, USA, and Oxygen, will break out into a standalone, publicly traded company

Matt Strauss and Donna Langley have been named to top roles at the new NBCUniversal, a move that pairs an executive well-versed in the world of streaming with a creative chief who has helped build and develop critical cinema franchises to help chart a new course for the venerable entertainment brand.