No. 5 Notre Dame defeated USC 49-35 on Saturday to put the program in prime position to reach the 12-team College Football Playoff next month. The Fighting Irish end the regular season with an 11-1 mark and are on the verge of reaching the CFP for the third time in program history.

For the second time in six years, all that stands in Notre Dame’s way from a spot in the College Football Playoff is a road trip to rival USC.

What to watch for as Notre Dame visits USC in this college football rivalry matchup, with our updated prediction for the game.

USC ranks 77th nationally with 16 turnovers. The Trojans turned it over 10 times in their five losses and six times in their six wins. Notre Dame has the nation's best turnover defense, forcing 26 on the season. Notre Dame ranks in the Top 10 in both fumbles recovered and interceptions. That makes the turnover battle in this game vitally important.

On Saturday, the USC Trojans ended their 2024 regular season with a 49-35 loss to the rival Notre Dame Fighting Irish. Following the defeat, some former USC football players took to social media to offer their thoughts.

USC women’s basketball has to know where Notre Dame’s Olivia Miles is on the floor at all times during Saturday’s huge game in the Galen Center.

Irish Breakdown makes predictions for the big rivalry matchup between the Notre Dame Fighting Irish and the USC Trojans

Want to watch the USC Trojans vs Notre Dame Fighting Irish in person on Saturday, Nov. 30? Tickets still remain for as little as $95.

No. 5 Notre Dame punched its ticket to the College Football Playoff with a 49-35 victory over Southern California for its 10th consecutive win

Christian Gray's 99-yard pick-6 with 3:39 remaining clinched No. 5 Notre Dame's 49-35 win over USC at the Los Angeles Memorial Coliseum on Saturday. With the victory, the Fighting Irish have locked up a spot in the College Football Playoff.

Notre Dame is one win away from the College Football Playoff. Follow along as they go for it today in Los Angeles